Mechanisms of Virologic Failure in Hepatitis C and Strategies for Treatment Failure

Mechanisms of Virologic Failure in Hepatitis C and Strategies for Treatment Failure

MOJ Immunol 2016, 4(1): 00114 have a low barrier to resistance, most patients may be successfully treated using DAA combination therapy. However, DAAs are vulnerable to drug resistance, and resistance-associated variants (RAVs) may naturally occur prior to DAA therapy or may emerge following drug exposure. While most RAVs are quickly lost in the absence of DAAs, compensatory mutations may reinf...

FAILURE MECHANISMS OF REFRACTORY LININGS FOR NONFERROUS FLASH SMELTING FURNACES

Although the flash smelting technologies use different furnace designs, the refractory linings are exposed to very similar aggressive environments and, as a result, the corrosion analysis results on one type of furnace could be generally applied to other furnaces of similar high temperature processes. Particularities regarding the different chemistries of the pyrometallurgical process and opera...

Retreatment of Hepatitis C Patients Who Previously Experienced Treatment Failure

comparison of zoe and vitapex for canal treatment of necrotic primary teeth

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CONCISE REVIEW IN MECHANISMS OF DISEASE Host Factors and Failure of Interferon- Treatment in Hepatitis C Virus

Failure of interferon(IFN) treatment in patients with chronic hepatitis C virus (HCV) infection is a challenging obstacle for clinical and experimental hepatology. Both viral and host factors have been implicated in reducing responsiveness to IFNtherapy. The role of viral factors has been studied extensively and has been summarized in several review articles; however, much less attention has be...